For which patient situation is metoclopramide the best choice for postoperative nausea and vomiting prophylaxis?

Metoclopramide is particularly effective for patients with a history of gastroesophageal reflux disease (GERD) because it increases gastrointestinal motility and enhances the tone of the lower esophageal sphincter. This action helps to facilitate gastric emptying and reduces the risk of vomiting, making it beneficial for patients who might experience nausea and vomiting related to their reflux condition.

In the context of postoperative care, patients with GERD are at an increased risk for nausea and vomiting owing to their condition. Metoclopramide's prokinetic properties can provide relief and help manage these symptoms effectively following surgery. Its effectiveness is further supported by its ability to mitigate the side effects of anesthesia and nausea, making it a suitable and targeted choice for such patients.

In contrast, other situations such as a history of seizures or bowel obstructions may require different approaches to postoperative nausea and vomiting due to safety and efficacy concerns.