Which medication should be avoided in patients with elevated T3 and T4 levels?

Amiodarone should be avoided in patients with elevated T3 and T4 levels due to its known impact on thyroid function. Amiodarone contains a high amount of iodine, which can affect the synthesis and secretion of thyroid hormones. In patients who are already hyperthyroid or have elevated levels of T3 and T4, the additional iodine and the pharmacological effects of amiodarone can exacerbate hyperthyroid conditions.

Furthermore, amiodarone can cause thyroiditis or worsen hyperthyroidism, leading to serious cardiovascular complications and other systemic effects due to the excess thyroid hormones. Therefore, it's crucial to take precautions when considering medications for patients with pre-existing thyroid imbalances, particularly when they are already presenting with elevated thyroid hormone levels.